Zanaflex is the prescription brand for tizanidine, a short-acting medication used to manage spasticity. Patients continuing Zanaflex 4 mg tablets should verify both the dosage form and the name authorized on the prescription because current U.S. labeling distinguishes the branded tablet from Zanaflex capsules and generic tizanidine products.
Sweetwater Medical Center transmits the submitted request through the pharmacy-assignment system. The assigned pharmacy validates the prescription, identifies whether brand Zanaflex or a permitted tizanidine product can be supplied, confirms the final amount, and dispenses and ships the medication.
Current Zanaflex Product Details

| Brand | Zanaflex |
|---|---|
| Active ingredient | Tizanidine hydrochloride, equivalent to tizanidine base |
| Current brand forms | 4 mg tablet; 2 mg, 4 mg and 6 mg capsules |
| Indication | Treatment of spasticity |
| Current labeler | Legacy Pharma USA, Inc. |
| Brand tablet package | 4 mg tablets in a 150-count bottle under current U.S. labeling |
| FDA status | FDA-approved prescription drug; initial U.S. approval in 1996 |
| Prescription status | Prescription required; not federally controlled |
The image is illustrative. The assigned pharmacy identifies the actual brand or generic product, dosage form, manufacturer, package and NDC before dispensing.
Tablet Request Prices for 2 mg and 4 mg
| Requested product | Package | Estimated price | Per tablet |
|---|---|---|---|
| Tizanidine 2 mg tablet | 30 tablets | From $37.99 | From $1.27 |
| Zanaflex or tizanidine 4 mg tablet | 30 tablets | From $44.87 | From $1.50 |
| Zanaflex or tizanidine 4 mg tablet | 60 tablets | From $73.32 | From $1.22 |
The prescription and available finished product determine whether the request is filled as brand Zanaflex or generic tizanidine.
Patients may submit an existing prescription, request an eligible transfer or select a $20 online medical consultation with Cody R. Christensen, DO, where available. A clinician issues or renews a prescription only when treatment is medically appropriate.
Prescription and account information is handled according to the Sweetwater Medical Center Privacy Statement.
What Zanaflex Treats During Spasticity Management
Zanaflex reduces excessive muscle tone associated with spasticity, including spasticity related to multiple sclerosis or spinal cord disease or injury. Its short duration can allow a prescriber to target times when relief is most important, but sedation, weakness and lower blood pressure may also affect mobility and daily activities.
Continue a Zanaflex Refill Without Changing the Product
Searches for a Zanaflex prescription refill often come from patients already stabilized on a particular form and food routine. The refill request should therefore carry the current prescription details rather than relying only on the word tizanidine.
Identify the Current Tablet or Capsule
Use the prescription label to confirm the brand or generic name, strength, dosage form and quantity requested.
Submit the Refill, Transfer or Consultation Request
Provide the ZIP code and current prescription information, request an eligible transfer or select an available consultation.
The System Assigns a Pharmacy for the Destination
An eligible pharmacy is assigned according to licensing, destination, service coverage and ability to process the request.
The Pharmacy Confirms Form and Substitution
The pharmacy reviews the prescription, checks product availability and applies only a substitution permitted by the prescription and applicable requirements.
Brand Zanaflex 4 mg Versus Generic Tizanidine
The current U.S. label lists brand-name Zanaflex as a 4 mg tablet and as 2 mg, 4 mg and 6 mg capsules. FDA-approved generic tizanidine products may also be available, but a generic must match the prescribed dosage form and strength. A request for brand-only dispensing should be written and processed accordingly.
The 2 mg tablet price shown above refers to a tizanidine tablet request, not a current 2 mg Zanaflex brand tablet. This distinction keeps the commercial offer aligned with present U.S. labeling while still allowing patients to submit the product named on their prescription.
Why the Tablet and Capsule Cannot Be Switched Casually
Zanaflex tablets versus capsules is not simply a preference about swallowing. Under fasting conditions their exposure is similar, but food changes absorption differently for the two forms. The prescriber and pharmacist should account for this if a patient needs a Zanaflex tablet and capsule substitution.
| Prescription detail | What must remain consistent |
|---|---|
| Dosage form | Continue the prescribed tablet or capsule unless the prescriber authorizes a change |
| Food routine | Take the medicine consistently with food or consistently without food |
| Strength and schedule | Follow the individualized titration and maximum daily directions on the prescription |
| Discontinuation | Taper when directed rather than stopping abruptly after regular or high-dose use |
When the Lower-Cost Zanaflex Option Is Not the Same Prescription
The cost difference between a branded tablet, branded capsule and generic tablet can be substantial. Before choosing an option based on price, compare the prescribed form, strength and quantity. A lower advertised amount for a generic tablet is not a valid replacement for a capsule prescription unless the change is clinically authorized.
Ciprofloxacin, Fluvoxamine and Sedating Medicines
Ciprofloxacin and fluvoxamine are contraindicated with Zanaflex because they can greatly increase tizanidine exposure, leading to severe hypotension, excessive drowsiness and impaired psychomotor function. A medication review should also cover blood-pressure medicines, other CYP1A2 inhibitors, alcohol, opioids, benzodiazepines and other central nervous system depressants.
- Common effects include dry mouth, drowsiness, weakness and dizziness.
- Blood pressure may fall, especially when standing or when other blood-pressure-lowering medicines are used.
- Liver testing is recommended at baseline and after the maximum dose has been reached.
- Abrupt discontinuation can cause rebound high blood pressure, a fast heartbeat and increased muscle tightness.
Call 911 if a patient collapses, cannot be awakened, has trouble breathing or develops a severe allergic reaction. Prompt medical assessment is also required for fainting, a very slow heartbeat, hallucinations or symptoms of liver injury such as yellow skin or eyes.
Medical Disclaimer
This page provides general information about Zanaflex, tizanidine product forms, estimated order prices and the partner-pharmacy process. It does not replace an examination, medication reconciliation, prescription or individualized titration plan.
Do not change between tablets and capsules, alter the food routine, increase the dose or stop regular tizanidine treatment without guidance from the prescriber.
Frequently Asked Questions About Zanaflex Orders and Refills
Can I refill my Zanaflex prescription online?
A patient may submit an existing prescription or request an eligible transfer or consultation. The exact form, strength and refill eligibility must be confirmed before dispensing.
Is brand-name Zanaflex 4 mg still available?
Current U.S. labeling lists a 4 mg Zanaflex tablet. Actual inventory is confirmed by the pharmacy assigned to the prescription request.
How much does Zanaflex 4 mg cost for 30 tablets?
The opening table shows an estimated amount for the displayed request. The final price depends on whether the prescription is filled with brand Zanaflex or an eligible generic tizanidine product.
Can a pharmacy substitute tizanidine for Zanaflex?
An FDA-approved generic may be substituted when permitted, but it must match the prescribed dosage form and strength. A brand-only instruction or a change of dosage form requires appropriate authorization.
Are Zanaflex tablets and capsules interchangeable at the pharmacy?
No automatic switch should be assumed. Food affects absorption differently, so a change between tablet and capsule forms should be reviewed by the prescriber and dispensing pharmacist.
Related Muscle Spasm and Medication Safety Information
Medical References
Pharmacist Review of Zanaflex Information
The medication information on this page, including the indication, current dosage forms, dosage range, prescription requirement, tablet and capsule distinction, contraindications, interactions, adverse effects and urgent warnings, was reviewed by Jeffrey Collins, PharmD, Pharmacist, Wyoming Pharmacist License 3836; NPI 1255701884.
This review applies to the general medication information and does not authorize an individual prescription, substitution or order. The assigned pharmacy remains responsible for validating the prescription, identifying the available product, confirming inventory and final price, and dispensing and shipping the medication.
Last pharmacist review: 08.12.2026.
